You, and your favorite pet, have an Endocannabinoid System.
It's a great system that wants us to be in homeostasis, or balance. Our biological systems are actively working to maintain conditions for health, within a narrow margin. The molecular Endocannabinoid System, or ECS, keeps our cells in that range. Cannabinoid receptors run throughout our body as part of the Endocannabinoid System regulating physiological operations including hunger, pain sensitivity, temperament, and memory. The ECS can be found in all vertebrate species and it's key components are:
- Cannabinoid Receptors
- Metabolic Enzymes that break down the Endocannabinoids after use
Your ECS is involved in regulation of a variety of very important physiological and cognitive processes, such as fertility, pregnancy during pre- and postnatal development, appetite, pain-sensation, mood and memory. Your ECS is key in mediating the pharmacological effects of cannabis, and CBD. "Endocannabinoids are defined as the endogenous ligands of cannabinoid receptors, CB1 and CB2, and a growing body of evidence has emerged on the role of the ECS in the regulation of several physiological conditions and various diseases."
The 2 major Cannabinoid Receptors, CB1 and CB2 listen to conditions outside the cell and are the informants when conditions change inside the cell to start the correct cellular response that is needed. CB1 Receptors are predominantly in the brain and nervous system, as well as peripheral organs and tissues, and interact with THC to get people "high". Your CB2 Receptors are abundant outside of the nervous system, including in the immune system, but both are found throughout the body.
Endocannabinoids are molecules that bind to the Cannabinoid Receptors and activate them, and are produced naturally by our cells. Endocannabinoids are made and used by our body, exactly when needed.